Isaac married Amy "Emma" Coffeen on 13 Jun 1782 (MARR) in Cavendish, Windsor, Vermont, United States. Amy (daughter of John Coffeen and Susannah Goldsmith) was born in 1761 in Topsfield, Topsfield, Essex, Massachusetts; died on 12 Apr 1832 in Cavendish, Windsor Co., Vermont, United States; was buried in Apr 1832 in Coffeen Cemetery, Cavendish, Windsor, Vermont, United States. [Group Sheet] [Family Chart]

1. Enos Baldwin was born on 28 Jun 1783 in Cavendish, Windsor, Vermont, United States; died on 18 May 1829 in Manhattan, New York City, New York, United States.
2. John Coffeen Baldwin was born on 29 Jun 1785 in Cavendish, Windsor, Vermont, United States; died on 5 Aug 1850 in Vermont, USA.
3. Emma Baldwin was born on 20 May 1787 in Cavendish, Windsor Co., Vermont, United States; died on 23 Jun 1878 in Cambridge, Middlesex Co., Massachusetts, United States; was buried in Jun 1878 in Cavendish, Windsor Co., Vermont, United States.
4. Abigail Baldwin was born in 1789; died in 1862.
5. Susanna Baldwin was born on 15 Apr 1791 in Cavendish, Windsor Co., Vermont, United States; died after 1819.
6. Isaac Baldwin was born in 1793 in of Cavendish, Windsor, Vt..
7. Thomas Baldwin was born in 1797 in Cavendish, Windsor, Vermont, United States; died in 1833 in Potsdam, St. Lawrence, New York, United States.
8. Pollard Baldwin was born on 22 Jan 1799 in Windsor Co, Vermont; died on 16 May 1858 in Ladoga, Montgomery, Ind.; was buried in 1858 in Ladoga, Montgomery, Indiana, United States of America.
9. Goldsmith Baldwin was born on 13 Jan 1804 in Cavendish, Windsor, Vermont, United States; died after 1850.
10. Elmira Baldwin was born on 13 Apr 1806 in Cavendish, Windsor, Vermont, United States; died on 10 Mar 1860 in Montpelier, Blackford, Indiana, United States; was buried in Woodlawn Cemetery, Blackford, Indiana, United States.
11. Zilpha Baldwin was born on 6 Jun 1807 in Cavendish, Windsor, Vermont, United States; died after 1825.